BİOMATBIOMATERIALS AND TISSUE ENGINEERING RESEARCH LABORATORY


Ezgi Antmen

 

 

Title:  PhD. in Biotechnology, METU
Education: 

MSc. Biological Sciences

B.Sc. Student in Molecular Biology and Genetics, METU

Contact: 

Telephone: +90 312 210 53 41

e-mail: ezgi.antmen@metu.edu.tr

 

 Responsible for the www-pages of BMDB

 

Research Field: 

 

Cell-Material Interactions

It was observed that cancerous and healthy cells show behavioral differences on surfaces with micro and nano features in their attachment, migration, proliferation and deformation. It was observed that nuclei of the cancer cells were deformed when they were seeded on certain micropatterned surfaces especially when the distance between the features was enough for a cell to slip in between two features. These differences are expected to be a key to understanding cancer cell behavior and detection. Several detection methods including lab-on-a-chip devices are being considered to make the process easy, reproducible and accurate, and to allow reduction in reagent consumption and process time.


Selected Publications:


Antmen E., Ermis M., Demirci U., Hasirci V. Effect of Micropatterned Surfaces on Cell Adhesion and Nuclear Deformation of Saos-2 Cells on PLGA and Collagen Films. BIOMED, October 22-24, 2015, Antalya, Turkey. (Poster Presentation).

Antmen E., Ermis M., Demirci U., Hasirci V. Effect of Micropatterned Surfaces on Cell Adhesion and Nuclear Deformation of Saos-2 Cells on PLGA and Collagen Films. FBPS, July 8-11, 2015, Riva Del Garda, Italy. (Oral Presentation).

Ermis M., Baran E. T., Dursun T., Antmen E., Hasirci V. Contribution of physical forces on the design of biomimetic tissue substitutes. Brennan, A. B., & Kirschner, C. M. (Eds.). (2014). Bio-inspired Materials for Biomedical Engineering. John Wiley & Sons, pp. 59-76, ISBN: 978-1-118-36936-4.

Ermis M., Antmen E., Gurkan U. A., Demirci U., Hasirci V. Effect of Micropatterned PLGA and Collagen Surfaces on Cell Adhesion and Nuclear Deformation. MRS Fall Meeting, December 1-6, 2013, Boston, MA, ABD. (Poster presentation).