Prof. Dr. Gamze Torun Köse



Title:  Prof. Dr.  (Yeditepe University, Dept. of Genetics and Bioengineering)
Education:  Ph.D. Biotechnology, METU, 2002
M.Sc. Biotechnology, METU, 1996
B.Sc. Biological Sciences, METU, 1994
Contact: e-mail:



Research Field


Tissue engineering (bone, cartilage, nerve, cardiac tissue), adult and embryonic stem cell, biodegradable polymers, liposomes, drug delivery, hard tissue repair, surface modification.


G. Köse CV



Selected Publications  


International Papers 

  • E.Can, A.I.Kanneci, G. Udenir, G.T.Köse, S.Bucak, Paclitaxel Release from PLLA/PCL Blends, Biomacromolecules, (submitted), 2011
  • M.Ramazanoglu, G.T.Köse, Nanotexturing of infrasurfaces, Frontiers in Biomaterials Science and Engineering, (submitted), 2011
  • M.Ramazanoglu, R.Lutz, P.Rusche, L.Trabzon, G.T.Köse, F. W.Neukam, K.A.Schlegel, Osteoconductive Effect of Combined Delivery of Bone Morphogenetic Protein-2 and Vascular Endothelial Growth Factor From Biomimetically Coated Implants, Bone (submitted), 2011.
  • M.Ramazanoglu,  A.Demirel, O.Gumru,  A.B.Ertan, E.D.Sam, M.Urgen, G.T.Köse, Increased cellular functions on microrough titanium surfaces having anatase nanotubular structures, Bio-medical Materials and Engineering (submitted), 2011
  • A.B.Ertan, P.Yılgor, B.Bayyurt, G.T.Köse*, V.Hasirci, Effect of Sustained Growth Factor Release on Cartilage Tissue Engineering, Journal of Tissue Engineering and Regenerative Medicine(submitted), 2011
  • H.Cimenoglu, M.Gunyuz, G.T.Köse, M.Baydogan, F.Ugurlu, C.Sener, Micro-Arc Oxidation of Ti6Al4V and Ti6Al7Nb Alloys for Biomedical Applications, Materials Characterization, doi: 10.1016/j.matchar.2011.01.002, 2011.
  • D.Yücel, G.T.Köse, V.Hasırcı, Tissue Engineered, Guided Nerve Tube Consisting of Aligned Neural Stem Cells and Astrocytes, Biomacromolecules,11, 3584–3591, 2010
  • H.Kenar, G.T.Köse, V.Hasırcı, Design of a 3D Aligned Myocardial Tissue Construct From Biodegradable Polyesters, J.Mater.Sci.Mater.Med., 21(3): 989-997, 2010
  • D.Yücel, G.T.Köse, V.Hasırcı, Polyester Based Nerve Guidance Conduit Design, Biomaterials31(7):1596-1603, 2010
  • M.E.Yalvac, M.Ramazanoglu, A.A.Rizvanov, F.Sahin, O.F.Bayrak, U.Salli, A.Palota´s, G.T. Köse, Isolation and characterization of stem cells derived from human third molar tooth germs of young adults: implications in neo-vascularization, osteo-, adipo- and neurogenesis,Pharmacogenomics Journal, 10, 105-113,  2010
  • N. Ozturk,  A. Girotti,  G. T. Köse,  J. C. Rodríguez-Cabello,  V. Hasirci, Development of A Novel Method For Dynamic Cell Culturing And Its Application To Micropatterned, ELP-Modified P-Nipam Scaffolds, Biomaterials, 30(29):5417-26, 2009
  • B.Başmanav, G.T.Köse, and V.Hasirci, Sequential Growth Factor Delivery From Complexed Microspheres For Bone Tissue Engineering, Biomaterials, Vol.29, 4195-4204, 2008
  • D.Yücel, H.Kenar, G.T.Köse, and V.Hasirci, Mesenchymal stem cell behaviour on topographical cues, Tissue Engineering Part A, Vol.15, Iss.5, Page 878, 2008
  • M.E.Yalvaç, M.Ramazanoğlu, O.F.Bayrak, F.Şahin and G.T.Köse, Multipotent stem cells derived from human dental follicle show osteogenic and neurogenic differentiation, FEBS Journal, Vol.275, Page 91, 2008  
  • M.E.Yalvaç, O.F.Bayrak, G.T.Köse and F.Şahin, Neuron-like cells derived from human cervical cancer HeLa cells, International Journal of Immunogenetics, Vol. 34 Issue 4 Page 287-299, 2007
  • H.Kenar, G.T.Köse, and V.Hasirci,  Tissue engineering of bone on micropatterned biodegradable polyester films,  Biomaterials  Vol.27, 885-895,  2006
  • G.T.Köse, F.Korkusuz, P.Korkusuz, N.Purali, A.Özkul, and V. Hasırcı, Bone generation on PHBV matrices: an in vitro study,  Biomaterials, Vol.24, pg. 4999-5007, 2003
  • G.T.Köse, H.Kenar, N.Hasırcı and V.Hasırcı, Macroporous Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) matrices for bone tissue engineering, Biomaterials, Vol. 24, 1949-1958, 2003
  • G.T.Köse, F.Korkusuz, S.Ber, and V. Hasırcı, Poly(3-hydroxybutyric acid-co-3-hydroxyvaleric acid) Based Tissue Engineering Matrices, Journal of Materials Science: Materials in Medicine, Vol.14, pg. 121-126, 2003
  • Tezcaner, G.T.Köse and V. Hasırcı, Fundamentals of Tissue Engineering: Tissues and Applications, Technology and Health care (Biomed 8 special issue), Vol.10 Iss. (3,4), pg. 203-216, 2002
  • G.T. Köse, A. Tezcaner and V. Hasırcı, Fundamentals of Tissue Engineering: Carrier Materials and an Application, Technology and Health care (Biomed 8 special issue), Vol.10 Iss. (3,4), pg. 187-201, 2002
  • G.T.Köse, M.Y.Arıca and V.Hasırcı, Low-Molecular-Weight Heparin-Conjugated Liposomes with Improved Stability and Hemocompatibility, Drug Delivery, 5, 257-264, 1997


Books and Book Chapters 


  • G.T. Köse and V.Hasırcı, Cartilage Tissue Engineering, in: Biomaterials: From Molecules to Engineered Tissues, N.Hasırcı and V.Hasırcı, Kluwer Plenum, London, UK, pp. 317-329, 2004
  • G.T. Köse and V. Hasırcı, Polymeric Biodegradable Hard Tissue Engineering Applications, in: Tissue Engineering and Biodegradable Equivalents: Scientific and Clinical Applications, D.L. Wise, Marcel Dekker, Inc., U.S.A, pp.301-315, 2002


Other Publications 


  • E.Can, G.T.Köse, M.Değertekin, S.Bucak, Polimerik Kalp Stentleri, TÜBİTAK Bilim Teknik Dergisi , Oct 2010.
  • G.T. Köse, F.Korkusuz, A.Özkul, S.Ber, H.Kenar and V. Hasırcı, Tissue Engineering of Bone Using Collagen and PHBV Matrices, Technology and Health care (Biomed 8 special issue), (Extended abstract). Vol.10 Iss. (3,4), pg. 299-301, 2002