Last Updated:
07/10/2025 - 18:19

Senem_Buyuksungur

Title

   Research Specialist, BIOMATEN, METU

  

  

Address

   BIOMATEN, ODTU, Biyoteknoloji Arastirma Laboratuvari
Universiteler Mh., Dumlupinar Blv. No:1 06800 Cankaya, Ankara, Turkey

     

Education

Ph.D.      2014-2019      Department of Biotechnology, Graduate School of Natural and Applied Sciences, Middle East Technical University, Ankara, Turkey
M.Sc.      2012-2014      Department of Biotechnology, Graduate School of Natural and Applied Sciences, Middle East Technical University, Ankara, Turkey
B.Sc.    2007-2011    Department of Biochemistry, Faculty of Science, Ege University, Izmir, Turkey

Publications

Buyuksungur, S., Tanir, T. E., Hasirci, V., and Hasirci, N. (2025). Antibacterial and Cell-Adhesive Poly (2-ethyl-2-oxazoline) Hydrogels Developed for Wound Treatment: In Vitro Evaluation. Biomacromolecules26(5), 3139-3154. DOI: 10.1021/acs.biomac.5c00181
 
Parau, A. C., Büyüksungur, S., Li, G., Liu, Q., Badillo, E., Blum, L., Schmidt, J., Pana, I., Vitelaru, C., Marinescu, I. M., Dinu, M., Smuglov, M., Schmuttermaier, C., Endogan-Tanir, T., Klüter, H., Hasirci, N., Kzhyshkowska, J., and Vladescu-Dragomir, A. (2025). Zn-doped CaP coating equips Ti implants with corrosion resistance, biomineralization, antibacterial and immunotolerant activities. Journal of Advanced Research. DOI: 10.1016/j.jare.2025.01.045
  
Basoz, D., Akalinli, A., Buyuksungur, S., Celebi, A. C., Yucel, D., Hasirci, N., and Hasirci, V. (2025). Preclinical Testing of 3D Printed, Cell Loaded Hydrogel Based Corneal Substitutes on Rabbit Model. Macromolecular Bioscience, 2400595. DOI: 10.1002/mabi.202400595
 
Basoz, D., Karaman, M. I., Buyuksungur, S., Yucel, D., Hasirci, N. E. S. R. İ. N., Kocaoglu, B., and Hasirci, V. (2024). 3D printed PCL-nHAp composite implants for the treatment of segmental bone defects: in vivo application in a rabbit model. Biofabrication17(1), 015041. DOI: 10.1088/1758-5090/ad9fe1
 
Buyuksungur, S., Parau, A. C., Dinu, M., Pana, I., Vitelaru, C., Schmidt, J., Endogan Tanir, T., Hasirci, V., Vladescu-Dragomir, A., and Hasirci, N. (2024). Variations of chemical, physical, mechanical properties, and biological and antimicrobial effectiveness of Ti alloys by coating with CaP doped with different amounts of Zn via micro-arc oxidation (MAO) technique. Ceramics International50(19), 37096-37110. DOI: 10.1016/j.ceramint.2024.07.100
  
Bostancı, N. S., Büyüksungur, S., Hasirci, N., and Tezcaner, A. (2024). Bioprinted scaffolds assembled as synthetic skin grafts by natural hydrogels containing fibroblasts and bioactive agents. International Journal of Polymeric Materials and Polymeric Biomaterials73(11), 927-945. DOI: 10.1080/00914037.2023.2230339
  
Gokyer, S., Monsef, Y. A., Buyuksungur, S., Schmidt, J., Vladescu Dragomir, A., Uygur, S., Oto, C., Orhan, K., Hasirci, V., Hasirci, N., and Yilgor, P. (2024). MgCa-Based Alloys Modified with Zn-and Ga-Doped CaP Coatings Lead to Controlled Degradation and Enhanced Bone Formation in a Sheep Cranium Defect Model. ACS Biomaterials Science & Engineering10(7), 4452-4462. DOI: 10.1021/acsbiomaterials.4c00358
  
Buyuksungur, S.Yilgor Huri, P., Schmidt, J., Pana, I., Dinu, M., Vitelaru, C., Kiss, A. E., Tamay, D. G., Hasirci, V., Vladescu, A., and Hasirci, N. (2023). In vitro cytotoxicity, corrosion and antibacterial efficiencies of Zn doped hydroxyapatite coated Ti based implant materials. Ceramics International, 49(8), 12570-12584. DOI: 10.1016/j.ceramint.2022.12.119
  
Schmidt, J., Pana, I., Bystrova, A., Dinu, M., Dekhtyar, Y., Vitelaru, C., Gorohovs, M., Marinescu, I. M., Yilgor Huri, P., Tamay, D. G., Juravlea, G. A., Buyuksungur, S., Parau, A. C., Hasirci, V., Hasirci, N., and Vladescu, A. (2023). Zn doped CaP coatings used for controlling the degradation rate of MgCa1 alloy: In vitro anticorrosive properties, sterilization and bacteria/cell-material interactions. Colloids and Surfaces B: Biointerfaces, 222, 113087. DOI: 10.1016/j.colsurfb.2022.113087
  
Bostancı, N. S., Buyuksungur, S., Hasrıcı, N., Tezcaner A. (2022) Potential of Pectin for Biomedical Applications: A Review, Journal of Biomaterials Science: Polymer Edition
  
Bostancı, N. S., Buyuksungur, S., Hasrıcı, N., Tezcaner A. (2022) pH Responsive Release of Curcumin from Photocrosslinked Pectin/Gelatin Hydrogel Wound Dressings, Materials Science and Engineering: C,  112717.
  

Buyuksungur, S., Hasirci, V., Hasirci, N. (2021). 3D printed hybrid bone constructs of PCL and dental pulp stem cells loaded GelMA. Journal of Biomedical Materials Research Part A. DOI: 10.1002/jbm.a.37235

  
Buyuksungur, S., Tanir, T. E., Buyuksungur, A., Bektas, E. I., Kose, G. T., Yucel, D., et al. (2017). 3D printed poly (ε-caprolactone) scaffolds modified with hydroxyapatite and poly (propylene fumarate) and their effects on the healing of rabbit femur defects. Biomaterials science, 5(10), 2144-2158. DOI: 10.1039/c7bm00514h
  
Polat, G.G., Akgun, O.M., Simsek, B., Saracli, M.A., Heper, S. and Hasirci, V. (2016) Fluoride-containing Anti-caries pH-sensitive Release System and Its Effect on Streptococcus Mutants. Fluoride 49(4 Pt 1):458-466.

Projects

2021-2022 Hastaya Ozel 3B Basilmis Deri Implantinin Gelistirilmesi    METU-BAP/GAP   Researcher
2016-2017   3B Yazici ve Liyofilizasyon ile Uretilmis Iskeleler Kullanılarak Kemik Tumoru Modeli Gelistirilmesi TUBITAK-POLAND   Scholarship
2014-2016 Doku Muhendisligi Yontemi ile Hastaya Ozel Ortopedik Implant Tasarimi ve Uretimi TUBITAK 1003   Scholarship
2014 Vucut Icine Yerlestirilen (Implantable) Norostimulasyon/Noromodulasyon Cihazlari Tasarimi ve Gelistirilmesi TUBITAK 1003 Scholarship

Proceedings & Symposia

Bostancı, S., Buyuksungur, S., Hasirci N., Tezcaner, A. (2021), Pektin ve Jelatin Esasli Biyoaktif Yara Ortusu Gelistirilmesi, 25. Ulusal Biyomedikal Bilim ve Teknoloji Sempozyumu (BIOMED 2021-TR), Ankara, Turkey (Online)        Oral Presentation
 
Buyuksungur, S., Hasirci N., Hasirci, V. (2019), 3D PCL/Gelma Hybrid Scaffolds in Bone Tissue Engineering, 24th International Biomedical Science and Technology Symposium (BIOMED 2019), Izmir, Turkey Poster Presentation
 
Buyuksungur, S., Buyuksungur, A., Hasirci N., Hasirci, V. (2018), Kemik Doku Muhendisliginde 3 Boyutlu PCL/GelMA Hibrit Iskeleler, 23. Biyomedikal Bilim ve Teknoloji Sempozyumu (BIOMED 2018-TR), Istanbul, Turkey Poster Presentation
  
Buyuksungur, S., Endogan, T. T., Buyuksungur, A., Bektas, E. I., Torun, K. G., Yucel, D., Beyzadeoglu T., Cetinkaya E., Yenigun C., Tönük E., Hasirci V., Hasirci, N. (2017), Polymeric composites with multifunctional properties and 3D bioplotted scaffolds for tissue engineering applications, 28th Annual Conference of the European Society for Biomaterials (ESB), Athens, Greece Oral Presentation
  
Buyuksungur A., Buyuksungur S., Hasirci N., Hasirci H. (2016), 3 Boyutlu Hastaya Ozel Biyobozunur Kemik Implantlarının Tasarimi ve Karekterizasyonu, MicroCT Summer School, Malatya, Turkey Oral Presentation
  
Buyuksungur A., Hasirci N., Hasirci H., Buyuksungur S. (2016), Biyobasım Sonrasi Implant Goruntulemesi: MikroCT, Doku Muhendisliginde Biyobasim: Polimerik Malzemeler, Biyoseramik Kompozitler, Doku Ozdesleri, Kocaeli University, Kocaeli, Turkey  Oral Presentation
  
Buyuksungur S., Hasirci N., Hasirci V., (2015), Controlled Doxorubicin Delivery from Photoresponsive Liposomes Carrying Vitamin A Derivatives, 21st International Biomedical Science and Technology Symposium (BIOMED 2015), Antalya, Turkey  Poster Presentation
  
Buyuksungur S., Buyuksungur A., Hasirci N., Hasirci V., (2015), 3D Printed, Tissue Engineered Femoral Implant Design and Production, 21st International Biomedical Science and Technology Symposium (BIOMED 2015), Antalya, Turkey Poster Presentation
  
Komez A., Buyuksungur S., Hasirci V., Hasirci N., (2015), Synthesis of Polyurethane for Coating of Neurostimulator, 21st International Biomedical Science and Technology Symposium (BIOMED 2015), Antalya, Turkey Poster Presentation
  
Heper S., Hasirci N., Hasirci V., (2015), Patient-Specific Orthopedic Implant Design and Production with Tissue Engineering Method, 11th International Symposium on Frontiers in Biomedical Polymers (FBPS ’15), Riva del Garda, Italy Poster Presentation

Awards

2018-2019 METU Graduate School of Natural and Applied Sciences Thesis Award