Isik et al. (2022) Turkish Bulletin of Hygiene and Experimental Biology
Isik, G.; Tezcaner, A.; Hasirci, N.; Kiziltay, A. (2022) Determination of doxorubicin amount conjugated to mPEG-b-PCL copolymer in two different media via pH sensitive hydrazone bond, Turkish Bulletin of Hygiene and Experimental Biology, 79 (2), 12-0, DOI: 10.5505/TurkHijyen.2022.04317
The aim of this study was to find the efficient medium to bind an anticancer drug, Doxorubicin (DOX), to a synthesized polymer, methoxy poly(ethylene glycol)-block-polycaprolactone (mPEG-b-PCL) via pH sensitive hydrazone bonds and to determine the amount of conjugated drug.