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BIOMATERIALS AND TISSUE ENGINEERING RESEARCH LABORATORY | BIOMAT

Prof. Nesrin Hasirci

Faculty

Last Updated:
29/04/2024 - 11:33

Nesrin_Hasirci  

Title

   

Advisory Committee Member, BIOMATEN, METU
Professor, Departments of Biomedical Engineering, Biotechnology, 
Micro & Nanotechnology, and Polymer Science & Technology, METU 

Address

    BIOMATEN, METU Research Park
Universiteler Mh., Dumlupinar Blv., No:1 06800 Cankaya, Ankara, Turkey

E-Mail

    nhasirci[at]metu.edu.tr
nhasirci[at]gmail.com

Phone

    +90 312 210 14 96

     

Full Curriculum Vitae (pdf Format)

Education
Ph.D.      1982      Department of Chemistry, Graduate School of Natural and Applied Sciences, Middle East Technical University, Ankara, Turkey
M.Sc.      1973      Department of Chemistry, Graduate School of Natural and Applied Sciences, Middle East Technical University, Ankara, Turkey
B.Sc.    1971    Department of Chemistry, Faculty of Arts and Science, Middle East Technical University, Ankara, Turkey

Selected Publications
Bostancı, N. S., Büyüksungur, S., Hasirci, N., and Tezcaner, A. (2023). Bioprinted scaffolds assembled as synthetic skin grafts by natural hydrogels containing fibroblasts and bioactive agents. International Journal of Polymeric Materials and Polymeric Biomaterials, 1-19. DOI: 10.1080/00914037.2023.2230339
 
Buyuksungur, S., Huri, P. Y., Schmidt, J., Pana, I., Dinu, M., Vitelaru, C., Kiss, A. E., Tamay, D. G., Hasirci, V., Vladescu, A., and Hasirci, N. (2023). In vitro cytotoxicity, corrosion and antibacterial efficiencies of Zn doped hydroxyapatite coated Ti based implant materials. Ceramics International, 49(8), 12570-12584. DOI: 10.1016/j.ceramint.2022.12.119
 
Schmidt, J., Pana, I., Bystrova, A., Dinu, M., Dekhtyar, Y., Vitelaru, C., Gorohovs, M., Marinescu, I. M., Huri, P. Y., Tamay, D. G., Juravlea, G. A., Buyuksungur, S., Parau, A. C., Hasirci, V., Hasirci, N., and Vladescu, A. (2023). Zn doped CaP coatings used for controlling the degradation rate of MgCa1 alloy: In vitro anticorrosive properties, sterilization and bacteria/cell-material interactions. Colloids and Surfaces B: Biointerfaces, 222, 113087. DOI: 10.1016/j.colsurfb.2022.113087
 
Bostancı, N. S., Büyüksungur, S., Hasirci, N., and Tezcaner, A. (2022). Potential of pectin for biomedical applications: A comprehensive review. Journal of Biomaterials Science, Polymer Edition, 33(14), 1866-1900. DOI: 10.1080/09205063.2022.2088525
    
Bahadir, G. B., Gollu, G., Ilkay, H., Bagriacik, U., Hasirci, N., and Bingol-Kologlu, M. (2022). LOCAL-IGF-1 and GH application IMPROVES germ cell histology, spermatogenesis and fertility after experimental testicular torsion and detorsion. Journal of Pediatric Urology, 18(4), 410-e1. DOI: 10.1016/j.jpurol.2022.07.001
    
Isik, G., Kiziltay, A., Hasirci, N., and Tezcaner, A. (2022). Lithocholic acid conjugated mPEG-b-PCL micelles for pH responsive delivery to breast cancer cells. International Journal of Pharmaceutics, 621, 121779. DOI: 10.1016/j.ijpharm.2022.121779
   
Kara, F., Aksoy, E. A., Aksoy, S., and Hasirci, N. (2022). Coating of silver nanoparticles on polyurethane film surface by green chemistry approach and investigation of antibacterial activity against S. epidermidis. Journal of Bioactive and Compatible Polymers, 37(3), 205-219. DOI: 10.1177/08839115221098056
   
Işik, G., Tezcaner, A., Hasirci, N., and Kiziltay, A. (2022). Determination of doxorubicin amount conjugated to mPEG-b-PCL copolymer via pH sensitive hydrazone bond. Turkish Bulletin of Hygiene & Experimental Biology/Türk Hijyen ve Deneysel Biyoloji, 79(2). DOI: 10.5505/TurkHijyen.2022.04317
    
Bostancı, N. S., Büyüksungur, S., Hasirci, N., and Tezcaner, A. (2022). pH responsive release of curcumin from photocrosslinked pectin/gelatin hydrogel wound dressings. Biomaterials Advances, 134, 112717. DOI: 10.1016/j.msec.2022.112717
   
Tamay, D. G., Gokyer, S., Schmidt, J., Vladescu, A., Yilgor Huri, P., Hasirci, V., and Hasirci, N. (2021). Corrosion Resistance and Cytocompatibility of Magnesium−Calcium Alloys Modified with Zinc- or Gallium-Doped Calcium Phosphate Coatings. ACS Applied Materials and Interfaces. DOI: 10.1021/acsami.1c16307
 
Buyuksungur, S., Hasirci, V., and Hasirci, N. (2021). 3D printed hybrid bone constructs of PCL and dental pulp stem cells loaded GelMA. Journal of Biomedical Materials Research Part A, 109(12), 2425-2437. DOI: 10.1002/jbm.a.37235
     
Çetinkaya, Ö. A., Çelik, S. U., Hasırcı, N., and Gürel, M. (2020). Effects of intraperitoneal administration of simvastatin on collagen deposition, inflammation level and wound tension in an experimental incisional wound model. Acta Oncologica Turcica, 53(1), 181-188. DOI: 10.5505/aot.2020.16768
   
Komez, A., Buyuksungur, A., Antmen, E., Swieszkowski, W., Hasirci, N., and Hasirci, V. (2020). A two-compartment bone tumor model to investigate interactions between healthy and tumor cells. Biomedical Materials, 15(3), 035007. DOI: 10.1088/1748-605X/ab6b31
 
Tamay, D. G., Dursun Usal, T., Alagoz, A. S., Yucel, D., Hasirci, N., and Hasirci, V. (2019). 3D and 4D Printing of Polymers for Tissue Engineering Applications, Enabling Biomaterials For New Biomedical Technologies And Clinical Therapies, Eds. H.Uludag, A.Pandit, L. Kuhn, Frontiers in Bioengineering and Biotechnology, 7, 164. DOI: 10.3389/fbioe.2019.00164
 
Hasturk, O., Ermis, M., Demirci, U., Hasirci, N., and Hasirci, V. (2019). Square prism micropillars on poly (methyl methacrylate) surfaces modulate the morphology and differentiation of human dental pulp mesenchymal stem cells. Colloids and Surfaces B: Biointerfaces, 178, 44-55. DOI: 10.1016/j.colsurfb.2019.02.037
    

Books
Hasirci, V. and Hasirci, N. (2024). Fundamentals of Biomaterials (2nd ed.), Springer New York, NY. ISBN 978-3031540455
   
Hasirci, N. and Hasirci, V. (eds.) (2022). Doku Mühendisliği, Hidrojeller ve Biyomürekkepler, 3-Boyutlu Organ Yapımı, ODTÜ, Ankara, ISBN: 978-975-429-418-7
    
Hasirci, N. and Hasirci, V. (2022). Biyomalzemelerin Temel İlkeleri, ODTÜ, Ankara, ISBN: 978-975-429-412-5
   
Hasirci, V. and Hasirci, N. (2018). Fundamentals of Biomaterials, Springer New York, NY. DOI: 10.1007/978-1-4939-8856-3

Selected Book Chapters
Kok, F. N., Hasirci, N., Hasirci, V. (2022). Doku Mühendisliği. In: Doku Mühendisliği, Hidrojeller ve Biyomürekkepler, 3-Boyutlu Organ Yapımı, 1-14, ODTÜ, Ankara, ISBN: 978-975-429-418-7.
    
Malikmammadov, E., Hasirci, N. (2018). Dual and multi-stimuli responsive polymers for biomedical applications. In: Smart Polymers and Their Applications, 255-278, Elsevier Woodhead Publications. ISBN 978-0-08-102416-4.
 
Ermis, M., Calamak, S., Calibasi, G., Guven, S., Durmus, G., Rizvi, I., Hasan, T., Hasirci N., Hasirci, V., Demirci, U (2018). Hydrogels as a New Platform to Recapitulate the Tumor Microenvironment. In: Handbook of Nanomaterials for Cancer Theranostics, 478-506, Elsevier. ISBN 978-0-08-055302-3

Selected Projects
2022-Present 3B Basimla Uretilen Yapay Korneanın In Vivo Uygulanması ve Translasyonu TUSEB Researcher
2021-Present Covid-19 Arastirmalari Icin Pulmoner Kan-Hava Bariyer Modelinin Gelistirilmesi ve Terapotik Ilac Taranmasi (MicroLung, SEA-EUROPE JFS20ST-040, Science & Technology) SEA-EU JFS
TUBITAK 1001		 Researcher
2021-Present Mikrodesenli Yuzey Uzerinde Sinir Doku Modeli Olusturulmasi, Akson Yonlendirme ve Sinir Hasari Iyilesme Sureclerinin Incelenmesi    TUBITAK 1001   Researcher
2019-Present   Biyobozunur Kraniyofasyal Defekt Implanti Gelistirilmesi TEYDEB 1501   Patent Holder
2018-2021 Biodegradable and Non-Biodegradable Orthopedic Implants with Bactericidal Coatings and Controllable Degredability (CoatDegraBac)

ERA.Net RUS Plus
TEYDEB 1509

 Researcher

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